Bioptigen Envisu R2200 Spectral Domain Ophthalmic Imaging System

OCT Imaging Device

OCT Imaging Device

(Also known as Optical Coherence Tomography (OCT) Scanner) Capabilities: Images up to 1.7mm deep in tissue (2.3mm in air) -1.6µm pixel resolution in tissue (2.3µm in air) -Equipped with three lenses • General Retina lens – for imaging of human*, or near-human size retina • Rat Retina lens – for imaging of rat retinal health • 12mm Telencentric Lens – for non-ocular tissue imaging – Detailed Specifications are provided on the Bioptigen webpage *(note: this device is not FDA approved for clinical use and we do NOT use this on live human subjects) Special Functions: Our Lab is equipped with an animal imaging kit specifically developed to aide in imaging of rat ocular tissues. • This includes a custom-built staging device to safely and repeatedly position rats for imaging • Specialized rat retina lens is tuned to rat anatomy & used to obtain the best possible images of rat retina. A custom positioning device has been developed in-house to allow imaging of the pia-arachnoid complex and outer surfaces of the brain. • This device has 3 axes of motion in a polar-coordinate system (phi, theta, and r) in order to allow for repeatable, custom positioning of any area of the brain. • When equipped with the 12mm Telencentric Lens, the positioning device can accommodate brains as small at rat to as large as adult human. (0-85mm radius travel)

Instron 5943 Mechanical Testing System

Instron Photo sized

1kN, Electromechanical, Single Column Tabletop System for Low-Force Universal Testing Features: • Load measurement accuracy: +/- 0.5% of reading down to 1/1000 of load cell capacity option (2580 Series load cells) • Up to 2.5 kHz data acquisition rate option simultaneous on load, extension, and strain channels • Speed range of 0.05 – 2500 mm/min (0.002 – 100 in/min) • Customizable Control Panel • Compatible with Bluehill® Software • Automatic transducer recognition for load cells and extensometers • Small footprint saves space • Thousands of optional grips and fixtures • Full CE compliance

TA Instruments ARG2 RheometerResized_20180619_111355_6699

The AR-G2 is an advanced controlled stress, direct strain and controlled rate rheometer with a magnetic-levitation thrust bearing and a drag cup motor to allow nanotorque control. The magnetic bearing allows frictionless axial support and measurement of ultra low torques from 0.03 uN-m up to 200 mN-m with a resolution of 1 nN-m. Velocities up to 300 rad/s with a displacement resolution of 25 nrad can be applied; dynamic frequency range is 7.5 x 10(-7) to 628 rad/s. Temperature control is achieved using a Peltier plate. Custom environmental chambers and grip plates have been created for multiple unique biological applications.

Shock Tube

Capabilities: Our shock tube can generate pressure waves approximating the Friedlander waveform for blast research. Human Infant Finite Element Model • Tube length of 15’ and internal diameter 6” • Driver overpressures ranging from 10 to 60+ PSI • Closed end or open ended testing • Diaphragm manually punctured using pneumatic activated arrowhead • Varied driver gases to create desired pressure profiles Instrumentation: 8 sensor ports along the length of the driven section of the tube allow for pressure measurements. • Pressure sampled at up to 1MHz • PCB Piezotronics pressure sensors

Optokinetic Tracking Behavioral Test Unit

Capabilities: This custom device was designed to assess functional visual acuity for animal studies. Rotating contrast grating causes head tracking behavior when acuity sufficient to see the pattern. Human Infant Finite Element Model • Supports rat and mouse vision testing • 360 degree stimulation • Allows both light and dark adapted vision testing through the use of neutral density filters and infrared camera to track animal behavior Software: In-house Matlab program uses Psychtoolbox to present drifting stimulus across four computer monitors. • Testing algorithm designed to eliminate testing bias from knowledge of drift direction • Contrast of grating varied automatically in a 2 down 1 up algorithm to assess visual acuity threshold • Spatial Frequency and Rotation Speed can be varied to test specifications.

Olympus CX41 Upright Microscope

Lab Microscope 1 sized

• Newly-developed infinity corrected Plan C Achromat objectives offer exceptional flatness producing sharp, clear images right up the edge of the field of view (4x, 10x, 40x, 100x oil). • Preset package economically priced for educational institutions (CX31 only). • F.N. 20 eyepieces (CX41 can be equipped with F.N. 20 or 22 eyepieces). • Anti-fungus treatment helps protect optical parts even in high humidity regions. • Inward-facing, quadruple (CX31), or quintuple (CX41) revolving nosepiece improves access and makes for quick, easy slide changes. • Fixed Abbe condenser NA 1.25, centerable and focusable for Köhler illumination. • A 6V/30W halogen bulb provides ample illumination for any observation. • Ergonomically designed frame with low positioned coarse and fine focusing controls, analyzer slot for linear polarized light (CX41 only), and convenient handgrips at the front and back for transportation; integrated field stop. • Built in left or right hand stage with rackless design (CX31 right hand only), low positioned X, Y controls with ergogrips to facilitate operation.

Olympus SZX16 Research Stereomicroscope

Lab Microscope 2 sizedThe SZX16 is designed for advanced research and has a maximum numerical aperture of 0.30, producing a resolution of 900 line pairs per millimeter. The SZX16 provides the largest zoom ratio of any stereo currently (April 2006) on the market 16.4:1. With this zoom ratio combined with a series of parfocal objectives (0.5x, 1x, 1.6x & 2x) the SZX16 can take you from macro to micro viewing.

High-Performance Modeling Computers

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Capabilities: The laboratory houses a number of high-performance computers utilized to perform mathematical & engineering analyses. Specifically these machines are dedicated to running complex Finite-Element (FE) codes. All machines are equipped with the following engineering analysis programs: • ABAQUS, ANSYS, & Hypermesh (FE Analysis) • Matlab (Mathematical Analysis) • Labview (Data Acquisition) • Solidworks (Computer-Aided Design) • Many other useful engineering softwares Machine Specifics: Primary Modeling PCs • Intel Core i7x-3930K 3.2 Ghz Hexa-Core CPU (12 virtual cores), 32GB DDR3 RAM, 1TB HDD, Nvidia Quadro Graphics with 2GB Dedicated VRAM • Intel Core i7x-980 3.33Ghz Hexa-Core CPU (12 virtual cores), 24GB DDR3 RAM, 1TB HDD, ATI Radeon HD 5700 Graphics with 1GB Dedicated VRAM Additional CAD/Modeling PCs • (4 PCs) – Intel Core i7 930 2.8Ghz Quad-Core CPU (8 virtual cores), 12GB DDR3 RAM, 1TB HDD, ATI Radeon HD 5700 Graphics with 1GB Dedicated VRAM • (1 PC) – Intel Core i7 3770 3.4Ghz Quad-Core CPU (8 virtual cores), 8GB DDR3 RAM, 1TB HDD, Nvidia Quadro Graphics Card with 2GB Dedicated VRAM