Publications

Acoustic Warnings Reduce Head Trauma

Congratulations to Mohammad Homayounpour, PhD Graduate of Dr. Andrew Merryweather’s Ergonomics and Safety group on his publication Cervical muscle activation characteristic and head kinematics in males and females following acoustic warnings and impulsive head forces published in Annals of Biomedical Engineering. Sex, head and neck posture, and cervical muscle preparation are contributing factors in the severity of head and neck injuries. However, it is unknown how these factors modulate the head kinematics. In this study, twenty-four (16 male and 8 female) participants experienced 50 impulsive forces to their heads with and without an acoustic warning. Both sex and warning type […]

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In Situ Mechanics of the Subarachnoid Space

Congratulations to PhD Graduate Nik Benko on his publication Mechanical characterization of the human pia-arachnoid complex published in the Journal of Mechanical Behavior and Biomedical Materials. In this study, Nik quantified the normal traction modulus of the pia-arachnoid complex (PaC) in five post-mortem human subjects using hydrostatic fluid pressurization in combination with optical coherence tomography. This study is the first to characterize the mechanics of the human pia-arachnoid complex and quantify material properties in situ. Data from the study suggest implementing a heterogeneous model of the brain-skull interface in computational models of TBI may lead to more realistic injury prediction. The full article can be found here: Benko N, Luke […]

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Impact Angle and Fall Height Effect Skull Fracture Patterns

Congratulations to Jiawei Yan on his recent publication The effect of impact angle and fall height on skujl fracture patterns in infants published in the Journal of Biomechanical Engineering. The objectives of this research were to utilize a newly developed linear elastic fracture mechanics finite element model of infant skull fracture to investigate the effect of impact angle and fall height on the predictions of skull fracture patterns in infants. Nine impact angles of right parietal bone impacts were simulated from three different heights onto a rigid plate. Impact angle significantly affected the fracture initiation site and orientation. Fall height significantly affected the fracture […]

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ABME Selects Colter Image for Cover

Congratulations to Jourdan Colter for getting her manuscript “Finite element design optimization of a hyaluronic acid-based hydrogel drug delivery device for improved retention” published in the Annals of Biomedical Engineering! Her figures were extremely high-quality and selected for the cover of the March 2018 issue. Dr. Barbara Wirostko from EyeGate Pharmaceuticals collaborated on the manuscript. Funding was provided by an SBIR Phase II award through the National Science Foundation (Award#IIP-1430921) and DoD W81XWH-14-C-0025.    

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Ocular Blast Injury paper published in IOVS

Congratulations to Dan Shedd for his publication “Long term temporal changes in structure and function of rat visual system after blast exposure” being accepted and published in IOVS. This long (13 typeset pages!) multifaceted manuscript is a culmination of his thesis and includes detailed imaging, protein analysis, behavior analysis, and histology of eyes after blast exposure. This work was a collaboration from many investigators (see full list in image below).  It was funded by DOD Award W81XWH-12-1-0243.

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New publication investigates the effect of cyclic loading on pediatric TBI

Our manuscript, “Cyclic Head Rotations Produce Modest Brain Injury in Infant Piglets” was recently accepted by Journal of Neurotrauma for publication in 2016. The paper evaluates the time-dependent response of axonal injury and extra-axial hemorrhage following a continuous or episodic cyclic head rotation as compared to a single head rotation. Authors on the paper are Brittany Coats (UofU) Gil Binenbaum (CHOP), Colin Smith (Edinburgh), Robert Peiffer (Scheie Eye Institute), Cindy Christian (CHOP), Ann-Christine Duhaime (Mass General), and Susan Margulies (UPENN). The ahead of print manuscript will be available on the J. Neurotrauma website. A link will be provided here once available

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New Publication on Modeling the PAC

Congratulations to Greg Scott for getting his final publication accepted into Biomechanics and Modeling in Mechanobiology, one of the premiere modeling journals in our field. The whopping 19-page journal publication titled Utilizing multiple scale models to improve predictions of extra-axial hemorrhage in the immature piglet is an outstanding effort that describes the development and validation of multiple scale models to improve predictions of subdural and subarachnoid hemorrhage. The work builds upon his previous publication characterizing the distribution and variability of the subarachnoid microstructures within a brain and across several brains.  The author submitted manuscript will be posted shortly in the Publications section […]

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OCT imaging of pia-arachnoid complex to be published in IEEE Medical Imaging

Congratulations to Greg Scott on the acceptance of his publication entitled Microstructural Characterization of the Pia-Arachnoid Complex Using Optical Coherence tomography. This research quantified the distribution of arachnoid trabeculae across the surface of the immature porcine brain.

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New publication in Journal of Mechanical Behavior and Biomedical Materials

Congratulations to Jourdan Colter, Jami Saffioti, Alex Williams, and Patrick Moran for publishing their collaborative effort titled, “Age-related changes in dynamic moduli of ovine vitreous.” The rapid degradation and low mechanical stiffness of vitreous makes it challenging to capture high rate properties quickly without interference from inertial and time-related artifacts. Our recent publication describes and validates an advanced rheometry technique that converts the immediate response of time-dependent data into high rate frequency-dependent data. The citation and approved copy of our manuscript can be found here.

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New Publication by P. Moran

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Biological sample preparation for SEM imaging of porcine retina by P. Moran and B. Coats published in March issue of Microscopy Today

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